Anxiety and Anxiolytic Drugs by Florian Holsboer, Andreas Ströhle PDF

By Florian Holsboer, Andreas Ströhle

ISBN-10: 3540225684

ISBN-13: 9783540225683

ISBN-10: 3540280820

ISBN-13: 9783540280828

The current quantity offers a finished assessment at the present nation of simple and scientific learn on Anxiety and Anxiolytic medications . utilizing newly built tools and methods researchers are actually starting to comprehend the molecular mechanisms of tension, anxiousness issues and their therapy. In parallel, new drug pursuits were generated and the 1st scientific stories with new compounds were begun. In 20 chapters written through various specialists within the box accomplished details on all proper themes is supplied.

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3 Animal Models . . . . . . . . . . . . . Genetically Based Animal Models of Anxiety . . . . . Selectively Bred Rat Lines . . . . . . . . . . Inbred Mouse Strains . . . . . . . . . . . Genetically Engineered Mice . . . . . . . . . ENU-Mutagenized Mice: The “Phenotype-Driven” Approach Experience-Related Models of Altered Emotionality . .

Selectively Bred Rat Lines . . . . . . . . . . Inbred Mouse Strains . . . . . . . . . . . Genetically Engineered Mice . . . . . . . . . ENU-Mutagenized Mice: The “Phenotype-Driven” Approach Experience-Related Models of Altered Emotionality . . . Early Life Stressors . . . . . . . . . . . . Chronic Mild Stress . . . . . . . . . . . . Learned Helplessness . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

4 . . . . . . . . . . . . . . . . . . . . 3 Tests for Anxiety . . . . . . . . . . . . . Behavioral Expression of Anxiety . . . . . . . . . Avoidance of Unprotected Areas as Index for Anxiety . . . Exploration: The Counterpart of Anxiety . . . . . . Risk Assessment: A Sensitive Indicator for Anxiolytic Activity? Flight-Related Behavior: A Dissociation Between Panic and Generalized Anxiety? . . Food Intake Inhibition . . . . . . . .

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Anxiety and Anxiolytic Drugs by Florian Holsboer, Andreas Ströhle


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