By C.M. Poser
It is a thoroughly new, totally up to date colour atlas-textbook of a number of sclerosis (MS). the 1st of its variety, it deals specified price for its illustrations and instructive textual content at the very newest diagnostic approaches for MS. The ebook opens with introductory and heritage info after which covers the pathogenesis of MS related to alteration of the blood-brain barrier. The part on prognosis covers IgG and oligoclonal bands within the cerebrospinal fluid; evoked strength reviews, together with visible, brainstem auditory, and somatosensory; MRI (magnetic resonance imaging), together with MRI differential analysis related to ADEM, MDEM, Lyme sickness, and HTLV-I spastic paraparesis; and puppy (positron emission tomography) and SPECT (single photon emission tomography). Concluding sections hide the gross, microscopic, and electronmicroscopic pathology of MS and the visible procedure in MS, regarding optic and retrobulbar neuritis; fundoscopy, and visible fields. contains bibliographic re ferences and index.
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Extra info for An Atlas of Multiple Sclerosis
Fulminant monophasic multiple sclerosis, Marburg’s type. J Neurol Neurosurg Psychiatr 1990;53:918–21 Keltner J, Johnson C, Spurr J, et al. Baseline visual field profile of optic neuritis. Arch Ophthalmol 1993;111:231–4 Khan S, Yaqub B, Poser C, et al. Multiphasic encephalomyelitis presenting as alternating hemiplegia. J Neurol Neurosurg Psychiatr 1995; 58:467–70 Kinnunen E, Valle M, Piiranen L, et al. Viral antibodies in MS: A nationwide co-twin study. Arch Neurol 1990;47:743–6 Kirk J. The fine structure of the CNS in multiple sclerosis.
Oil red–O stain ©1998 CRC Press LLC Figure 39 Histology of an early multiple sclerosis plaque shows gemistocytic astrocytes, seen with H & E–Luxol fast blue (upper) and Golgi (lower) staining Figure 40 Biopsy specimen of a large cerebral plaque that was erroneously diagnosed as an astrocytoma. Note the large collection of macrophages. Periodic acid–Schiff (PAS) stain. (Figure 71 shows the CT scan of this patient) ©1998 CRC Press LLC Figure 41 Biopsy specimen of a deep thalamic plaque misdiagnosed as a brain tumor, as seen by Bodian (upper) and phosphotungstic acid– hematoxylin (PTAH; lower) stains.
II. Vesicular demyelination in an acute case. Neuropathol Appl Neurobiol 1979;5:289–94 Kurtzke J, Gudmundsson K, Bergmann S. Multiple sclerosis in Iceland. I. Evidence of a postwar epidemic. Neurology 1982;32:143–50 Hanemann C, Kleinschmidt A, Reiffenberger G, et al. Baló’s concentric sclerosis followed by MRI and positron emission tomography. Neuroradiology 1993;35:578–80 Kurtzke J, Hyllested J. Multiple sclerosis in the Faroe Islands. I. Clinical and epidemiological features. Ann Neurol 1979;5:6–21 Hickey W.
An Atlas of Multiple Sclerosis by C.M. Poser