Max Michael III, W. Thomas Boyce, Allen J. Wilcox's Biomedical Bestiary: An Epidemiologic Guide to Flaws and PDF

By Max Michael III, W. Thomas Boyce, Allen J. Wilcox

ISBN-10: 0316569518

ISBN-13: 9780316569514

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Extra info for Biomedical Bestiary: An Epidemiologic Guide to Flaws and Fallacies in the Medical Literature

Example text

Andereck, N. , and Tyler, C. W. Child abuse in Georgia: A method to evaluate risk factors and reporting bias. ]. Public Health 72:1353, 1982. Voluntary case reporting can result in erroneous conclusions about the demography ofchild abuse. Other conditions that are voluntarily reported are subject to the same potential problems. This type of response bias can be reduced by an inexpensive follow-up system described in this article. Mann,J. M. A prospective study of response error in food history questionnaires: Implications for food borne outbreak investigation.

Med. 298:1196, 1978. 4. Response Bias Response Bias is one of the more insidious creatures you are likely to encounter in your journeys through the medical literature. She will systematically undennine a research protocol by luring subjects into forgetfulness and inaccuracy-deliberate and unintentional. Pigtailed and cloaked in innocence, she insinuates herself into even the most sophisticated research designs. Her trick is always the same: she mysteriously influences how people respond to an investigator's questions so that their answers are distorted.

Some loss of study subjects is to be expected in any study. However, the larger the proportion of persons lost or excluded, the larger the possibility that those included are a biased sample. Selection bias can intervene even after study subjects have been enlisted in the research project. It is a rare study that doesn't lose some subjects along the way. People quit, die, or move away. It is very likely that the persons who are lost will differ in important ways from those who remain. As a general rule, the more subjects who are lost, the less useful are the results from the remainder.

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Biomedical Bestiary: An Epidemiologic Guide to Flaws and Fallacies in the Medical Literature by Max Michael III, W. Thomas Boyce, Allen J. Wilcox


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