Hans G. Vogel's Drug Discovery and Evaluation: Pharmacological Assays PDF

By Hans G. Vogel

ISBN-10: 3540709959

ISBN-13: 9783540709954

ISBN-10: 3540714200

ISBN-13: 9783540714200

The hot variation of this profitable reference deals either state of the art and vintage pharmacological tools. completely revised and extended to 2 volumes, it bargains an up to date collection of the main often used assays for reliably detecting the pharmacological results of capability medicinal drugs. each bankruptcy has been up to date, and various assays were further. all of the greater than 1,000 assays contains a close protocol outlining function and motive, and a serious evaluation of the implications and their pharmacological and medical relevance.

Show description

Read Online or Download Drug Discovery and Evaluation: Pharmacological Assays PDF

Best toxicology books

Download PDF by Andre Menez: The Subtle Beast: Snakes, From Myth to Medicine (Science

Textual content introduces readers to the advanced and soaking up international of snakes. comprises the starting place, positive factors, and type of snakes; an outline of snake venoms and their elements; a proof of ways venoms are important to us; and describes a variety of legendary and supernatural ideals approximately snakes. Hardcover, softcover on hand.

New PDF release: Safety Evaluation in the Development of Medical Devices and

Gad Consulting prone, Cary, NC. Serves as a pragmatic consultant for these chargeable for or enthusiastic about making sure safeguard within the use and manufacture of clinical units. Introduces present charts and information for all points of hazard evaluate. prior variation isn't brought up. Expanded-outline layout.

Waldemar M. Dabrowski, Zdzislaw E. Sikorski's Toxins in Food (Chemical & Functional Properties of Food PDF

Whereas platforms resembling GMP and HACCP guarantee a excessive normal of nutrition caliber, foodborne poisonings nonetheless pose a significant threat to the consumer's healthiness. the inability of data between a few manufacturers and shoppers concerning the hazards and merits concerning nutrients makes it crucial to supply up-to-date details so as to enhance meals security.

Molecular Modelling and Drug Design - download pdf or read online

Where of molecular modelling in drug layout is now firmly proven. This ebook includes chapters from younger scientists in and academia. They current the various new tools on hand in addition to describing the proper use of extra validated options. The booklet makes an attempt to mix optimism, together with equipment designed to semi-automate a wide a part of the drug layout strategy, with pragmatism, declaring many of the traps into which the unwary researcher can be drawn.

Extra resources for Drug Discovery and Evaluation: Pharmacological Assays

Sample text

Receptor Binding Assay for FSH . . . . . . . . Luteinizing Hormone (LH) = Interstitial Cell Stimulating Hormone (ICSH) . . . . . . . . . . . . Prostate Weight in Hypophysectomized Rats . . . . . Superovulation in Immature Rats . . . . . . . . Ascorbic Acid Depletion of Ovaries in PMSG/hCG-Primed Rats . . . . . . . . . Testosterone Production by Leydig Cells in Vitro Induced by LH . . . . . . . . . . . Receptor Binding Assay for LH . . . .

Inhibition of HCl Secretion . . . . . . . . . Anticholinergic Activity . . . . . . . . . . General Considerations . . . . . . . . . . Acetylcholine Receptor Binding . . . . . . . . H2 -Antagonism . . . . . . . . . . . . General Considerations . . . . . . . . . . Histamine H2 -Receptor Binding . . . . . . . . H2 -Antagonism in Isolated Guinea Pig Right Atria . . . H2 -Antagonism in Isolated Rat Uterus . . .

Propulsive Gut Motility in Mice . . . . . . . . Nerve-Jejunum Preparation of the Rabbit . . . . . Motility of Gastrointestinal Tract in Dogs . . . . . Thiry–Vella Fistula . . . . . . . . . . . Continuous Recording of Mechanical and Electrical Activity in the Intestine of Conscious Dogs . . . . . . . Absorption . . . . . . . . . . . . . Everted Sac Technique . . . . . . . . . . Stomach Emptying and Intestinal Absorption in Rats . .

Download PDF sample

Drug Discovery and Evaluation: Pharmacological Assays by Hans G. Vogel


by William
4.1

Rated 4.03 of 5 – based on 19 votes